Walter Bishop and William Bell are the most intelligent scientist alive. They could explain or create supernatural events with science. They made their labratory as a playground to discover other universes. Walter Bishop then realized that his brain is triggering him to tamper the structure of nature and causing hazardous problems for the future, like the cortexiphan trials. According to Bishop's theory, if he removes the certain parts of his brain, he would stop the cruelty.
As Observers, - highly intelligent specie that was developed by scientists. They also have a brain chip attached to their spinal cords. That brain chip gives them the ability to walk through time, teleport and read minds. The brain chip is the essence, or the source of becoming an observer. The observers, do not feel any emotions or empathy because of the brain chip.
Now, I correlate Walter Bishop's certain parts of his brain to this brain chip. They both blocks emotions and lead you to become a highly intelligent robot. Fear, hatred, love, jealousy, anger, happiness...
What makes us human essentially is empathy, the emotional intelligence. Without our emotions we wouldn't know where to stop. There will be no good or bad, there will only be goals, tasks, missions to complete. We would perceive music as just random rhythms and sounds, meaningless many sounds.
High Intelligence should always prioritize emotions. Without emotions, we have no control mechanism.